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View All Genomic Data PBM Motif Data PBM Clones Minimize All

-Genomic Data for Gli3				Links
Protein Gli3	UniPROBE Accession Number UP00540	Species Mus musculus	Domain zf-H2C2_2	Swiss-Prot Q61602
Name and Synonyms Name: GLI-Kruppel family member GLI3. Synonyms:Transcriptional activator GLI3; add, AI854843, AU023367, Bph, brachyphalangy, GLI3-190, GLI3FL, Pdn, Xt, Zinc finger protein GLI3				IHOP 121301
				NCBI RefSeq NP_032156
Description Has a dual function as a transcriptional activator and a repressor of the sonic hedgehog (Shh) pathway, and plays a role in limb development. The full-length GLI3 form (GLI3FL) after phosphorylation and nuclear translocation, acts as an activator (GLI3A) while GLI3R, its C-terminally truncated form, acts as a repressor. A proper balance between the GLI3 activator and the repres				JASPAR None Available

-PBM Motif Data for Gli3
Primary Motif Reverse Complement (RC)				Primary PWM Save
				Top Kmer GACCACCC E.S. 0.498 GGGTGGTC E.S. 0.498
Secondary Motif Reverse Complement (RC)				Secondary PWM Save
				Top Kmer GCCACCCA E.S. 0.495 TGGGTGGC E.S. 0.495
Primary Motif Reverse Complement (RC)				Primary PWM Save
				Top Kmer GACC.CCCA E.S. 0.497 TGGG.GGTC E.S. 0.497
Secondary Motif Reverse Complement (RC)				Secondary PWM Save
				Top Kmer C.CGG.GGTC E.S. 0.493 GACC.CCG.G E.S. 0.493
PBM-Derived DNA Binding Site Motif (BEEML-PBM) (AMADID # 015681) Reverse Complement (RC)				PWM Save
				Consensus NKVCCHCMNN NNKGDGGBMN
PBM-Derived DNA Binding Site Motif (BEEML-PBM) (AMADID # 016060) Reverse Complement (RC)				PWM Save
				Consensus KVCCNCMNNN NNNKGNGGBM
Downloads Download the zip of all Gli3 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.

-Gli3 Datasets
Gene	Clone Type	Last Modified	Save	View
Gli3	DNA binding domain only	2014-09-06
Gli3 Insert Sequence 1    ADKDESKQEP EVIYETNCHW EGCTREFDTQ DQLVHHINND HIHGEKKEFV 51   CRWLDCSREQ KPFKAQYMLV VHMRRHTGEK PHKCTFEGCT KAYSRLENLK 101  THLRSHTGEK PYVCEHEGCN KAFSNASDRA KHQNRTHSNE KPYVCKIPGC 151  TKRYTDPSSL RKHVKTVHGP EAHVTKKQRG DMHPRPPP
References Data are analyzed by array designs with AMADID #s 016060, 015681 in Peterson et al., Genes Dev 2012