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| -Genomic Data for E2f4 |
Links |
- Protein
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- UniPROBE Accession Number
- UP01362
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- Species
- Mus musculus
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- Domain
- E2F_TDP
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- Swiss-Prot
- Q8R0K9
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- Name and Synonyms
- Name: transcription factor E2F4.
Synonyms:2010111M04Rik, AI427446, E2F-4, Transcription factor E2F4
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- IHOP
- 144686
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- NCBI RefSeq
- NP_683754
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- Description
- Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
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- JASPAR
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None Available
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| -PBM Motif Data for E2f4 |
- PBM-Derived DNA Binding Site Motif
(Seed-And-Wobble)
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- PWM
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Save
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- Top Kmer
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AA.CGCGCG E.S. 0.465
CGCGCG.TT E.S. 0.465
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- Downloads
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Download the
zip
of all E2f4 PBM files
or view the downloads directory for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -E2f4 Datasets |
| Gene |
Clone Type |
Last Modified |
Save |
View |
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E2f4 |
DNA binding domain only |
2017-05-12 |
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- E2f4 Insert Sequence
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1 AEAGPQAPPP PGTPSRHEKS LGLLTTKFVS LLQEAKDGVL DLKLAADTLA
51 VRQKRRIYDI TNVLEGIGLI EKKSKNSIQW KGVGPGCNTR EIADKLI
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- References
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Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017
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