-Genomic Data for Rarg Links
Protein
UniPROBE Accession Number
UP01389
Species
Mus musculus
Domain
zf-C4
Name and Synonyms
Name: Retinoic acid receptor gamma.
Synonyms:AI385767, MGC11555, MGC18523, Nr1b3, Nuclear receptor subfamily 1 group B member 3, RARD, RAR-gamma, RARgamma2, RAR gamma 2
Description
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors (By similarity). Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function.
-PBM Motif Data for Rarg
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
AAGGTCAC
PWM
Save
Top Kmer
AAGGTCAC E.S. 0.491
GTGACCTT E.S. 0.491
Downloads
Download the zip of all Rarg PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-Rarg Datasets
Gene Clone Type Last Modified Save View
Rarg DNA binding domain only 2017-05-12 search save
Rarg Insert Sequence
1    ELVPSPPSPL PPPRVYKPCF VCQDKSSGYH YGVSACEGCK GFFRRSIQKN
51   MIYTCHRDKN CVINKVTRNR CQYCRLQKCF EVGMSKESVR NDRNKKKKEP
101  SKQECTE



References
Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017


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