Positions Available


  • There is a technical research assistant position available for a highly motivated individual with prior on-the-job experience in a molecular biology research lab. This position will focus on studies of human protein-DNA interactions and DNA regulatory elements by a combination of biochemical and cell culture based approaches. These data will aid in understanding mechanisms of transcriptional gene regulation and the impact of coding and noncoding genetic variation.


    Required skills include: preparation of solutions and media, growth of bacterial cultures, DNA mini- and midi-preps, preparation of DNA samples for Sanger sequencing and analysis of sequencing results, transformation of bacterial cells, preparation of E. coli glycerol stocks, restriction enzyme based or Gateway recombinational DNA cloning, PCR, DNA and protein gel electrophoresis, Coomassie staining of protein gels, Western blots. Prior experience with the following techniques would be helpful: expression and purification of recombinant proteins, preparation of Illumina sequencing libraries, DNA and protein sequence analysis, protein-DNA binding assays, mammalian cell culture, chromatin immunoprecipitation (ChIP), CRISPR/Cas genome editing. Other duties will include maintaining equipment and supplies.


    This position provides an excellent opportunity to be involved in cutting-edge research in gene regulation and genomics, and offers a stimulating, academic environment, and the opportunity to work in a team setting involving experimental and computational scientists. This position also offers the opportunity to gain valuable research skills, and written and oral communication skills. This position is ideal for a recent college graduate seeking to gain additional laboratory research experience.


    A recent Bachelor of Science degree in a biological science or related field is required. Applicants with a Bachelor’s degree in another area of concentration may be considered if the applicant has had significant coursework in the sciences, has the required prior laboratory work experience, and demonstrates strong potential. Applicant must have basic Linux proficiency and some computer programming experience.


    The Bulyk Lab is in the Division of Genetics at Brigham & Women’s Hospital, part of the Harvard Medical School research community located at the Longwood Medical Area in Boston, MA. We offer competitive salaries and benefits, and a highly interactive academic environment.


    To apply for this position, please submit a cover letter, CV and contact information for 3 references via the Mass General Brigham Careers website, Job Number RQ4082415: https://massgeneralbrigham.wd1.myworkdayjobs.com/en-US/MGBExternal.


    Please be sure to indicate in your cover letter if you would require visa sponsorship.

  • We have two postdoctoral positions available for highly motivated individuals with experimental and computational experience who are interested in transcriptional gene regulation. Our lab is interested in understanding how regulatory information is encoded in the genome, how that information is read out to regulate gene expression programs, and how genetic variation alters gene regulation.


    This project will employ biochemical, cell culture based, and computational approaches to investigate human transcription factor-DNA interactions, with a focus on determining the effects of coding variation in transcription factors. This project will employ a range of techniques including but not limited to: DNA cloning; protein expression; mammalian cell culture; genome editing; CUT&RUN or ChIP-Seq; RNA-Seq; PADIT-seq ; DNA and protein sequence analysis; computational analysis of human genetic variation data, Illumina DNA sequencing data and protein structure; and ML/AI. Postdoc position #1 is focused primarily on high-throughput biochemical assays, while postdoc position #2 is focused primarily on genome editing and cell culture based functional genomic assays. Both positions involve computational analysis.


    For both positions, applicants should have a recent Ph.D. (2025 or 2026), or will graduate in Fall 2026, in a biological field with strong quantitative skills and prior programming experience. Solid command of spoken and written English is required.


    The Bulyk Lab is in the Division of Genetics at Brigham & Women’s Hospital, part of the Harvard Medical School research community located at the Longwood Medical Area in Boston, MA. We offer competitive salaries and benefits, and a highly interactive academic environment.


    Applicants should email a cover letter and CV to: Prof. Martha L. Bulyk, Harvard Medical School Veritas Science Center Rm 466D, 77 Avenue Louis Pasteur, Boston, MA 02115; mlbulyk[at]genetics.med.harvard.edu. In the cover letter, indicate for which postdoc position you are applying, explain why you want to join my lab, and provide your anticipated start date, desired duration for the postdoc position, and longer-term career goals.


    Please be sure to indicate in your cover letter if you would require visa sponsorship.

  • There are positions available for graduate and medical students interested in computational and/or experimental genomics, including technology development. (Please read this if you are interested in working with me but are not yet a student in a graduate program at Harvard or MIT.) Graduate students outside of one of the graduate programs of which I am a member should first contact their graduate program director(s) to find out what their program rules are regarding doing a rotation and Ph.D. research in my lab.

  • There are research positions available for undergraduate students interested in experimental and/or computational genomics. Highly motivated students are encouraged to apply by sending an email, including a curriculum vitae. In the email, indicate your desired start date and approximate number of hours per week available for research.



    • Inquiries regarding other positions should be addressed to:
      mlbulyk [at] genetics [dot] med [dot] harvard [dot] edu