Protein Details

-Genomic Data for AFT1				Links
Protein AFT1	UniPROBE Accession Number UP00344	Species Saccharomyces cerevisiae	Domain AFT	Uniprot P22149
Synonyms Activator of iron transcription protein 1, AFT1, Iron-regulated transcriptional activator AFT1, YGL071W				IHOP 33132
				RefSeq NP_011444
Description Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability				SGD YGL071W

-PBM Motif Data
Primary Motif (Seed-and-Wobble)				Primary PWM View Save
Primary Motif (Seed-and-Wobble)				Top Kmer A.TGCACCC E.S. 0.483 GGGTGCA.T E.S. 0.483
Primary Motif (BEEML-PBM) (AMADID # 015681)				Primary PWM View
Primary Motif (BEEML-PBM) (AMADID # 015681)				Consensus NNNNNNNNNB VNNNNNNNNN
Downloads Download the zip of all Aft1 PBM files or view the downloads directory for individual files.
Link to TFBSshape This link will take you to the corresponding entry for Aft1 in TFBSshape, a database which provides information about the shape of the DNA at transcription factor binding sites. http://rohslab.cmb.usc.edu/TFBSshape/?tfid=&geneID344&sourceDB=uniprobe

-Annotations
Target Gene Functional Category Enrichment 1) FunSpec analysis run with p<0.005 without Bonferroni correction (view) 2) FunSpec analysis run with p<0.05 with Bonferroni correction (view)
Conditional Specificity 1) Specific conditions (view) 2) Condition categories (view)

-AFT1 Datasets
Clone ID	Clone Type	Last Modified	Save	View
y1009	Full length clone	2016-03-24
Insert sequence 1 MEGFNPADIE HASPINSSDS HSSSFVYALP KSASEYVVNH NEGRASASGN 51 PAAVPSPIMT LNLKSTHSLN IDQHVHTSTS PTETIGHIHH VEKLNQNNLI 101 HLDPVPNFED KSDIKPWLQK IFYPQGIELV IERSDAFKVV FKCKAAKRGR 151 NARRKRKDKP KGQDHEDEKS KINDDELEYA SPSNATVTNG PQTSPDQTSS 201 IKPKKKRCVS RFNNCPFRVR ATYSLKRKRW SIVVMDNNHS HQLKFNPDSE 251 EYKKFKEKLR KDNDVDAIKK FDELEYRTLA NLPIPTATIP CDCGLTNEIQ 301 SFNVVLPTNS NVTSSASSST VSSISLDSSN ASKRPCLPSV NNTGSINTNN 351 VRKPKSQCKN KDTLLKRTTM QNFLTTKSRL RKTGTPTSSQ HSSTAFSGYI 401 DDPFNLNEIL PLPASDFKLN TVTNLNEIDF TNIFTKSPHP HSGSTHPRQV 451 FDQLDDCSSI LFSPLTTNTN NEFEGESDDF VHSPYLNSEA DFSQILSSAP 501 PVHHDPNETH QENQDIIDRF ANSSQEHNEY ILQYLTHSDA ANHNNIGVPN 551 NNSHSLNTQH NVSDLGNSLL RQEALVGSSS TKIFDELKFV QNGPHGSQHP 601 IDFQHVDHRH LSSNEPQVRS HQYGPQQQPP QQLQYHQNQP HDGHNHEQHQ 651 TVQKDMQTHE SLEIMGNTLL EEFKDIKMVN GELKYVKPED