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| -Genomic Data for NOTCH2 |
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- Protein
- NOTCH2
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- UniPROBE Accession Number
- UP00481
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- Species
- Homo sapiens
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- Domain
- None Available
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- Swiss-Prot
- Q04721
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- Name and Synonyms
- Name: notch 2.
Synonyms:hN2; AGS2; HJCYS
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- IHOP
- 90629
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- NCBI RefSeq
- NP_077719.2
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- Description
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptot
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- JASPAR
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None Available
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH2_FigS1 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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C..TGGGAAC E.S. 0.495
GTTCCCA..G E.S. 0.495
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NNVTGDGARN
NYTCHCABNN
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- Downloads
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Download the zip
of all MAML1-CSL-GST-NOTCH2_FigS1 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH2_Fig5 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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CC.TGGGAA E.S. 0.492
TTCCCA.GG E.S. 0.492
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NBVTGRGAAH
DTTCYCABVN
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- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH2_Fig5 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -NOTCH2 Datasets |
| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH2 |
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| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH2_FigS1 | AMADID # 015681 |
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| MAML1-CSL-GST-NOTCH2_Fig5 | AMADID # 015681 |
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| Gene |
Clone Type |
Last Modified |
Save |
View |
| NOTCH2 |
Not full length |
2016-03-24 |
N/A
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N/A
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- Insert Sequence
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1 KRKHGSLWLP EGFTLRRDAS NHKRREPVGQ DAVGLKNLSV QVSEANLIGT
51 GTSEHWVDDE GPQPKKVKAE DEALLSEEDD PIDRRPWTQQ HLEAADIRRT
101 PSLALTPPQA EQEVDVLDVN VRGPDGCTPL MLASLRGGSS DLSDEDEDAE
151 DSSANIITDL VYQGASLQAQ TDRTGEMALH LAARYSRADA AKRLLDAGAD
201 ANAQDNMGRC PLHAAVAADA QGVFQILIRN RVTDLDARMN DGTTPLILAA
251 RLAVEGMVAE LINCQADVNA VDDHGKSALH WAAAVNNVEA TLLLLKNGAN
301 RDMQDNKEET PLFLAARE G SYEAAKILLD HFANRDITDH MDRLPRDVAR
351 DRMHHDIVRL LDEYNVTPSP PGTVLTSA
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- References
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Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010
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