-Genomic Data for NOTCH4 Links
Protein
NOTCH4
UniPROBE Accession Number
UP00483
Species
Homo sapiens
Domain
None Available
Name and Synonyms
Name: notch 4.
Synonyms:INT3; FLJ16302; MGC74442
Description
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptot
-PBM Motif Data for MAML1-CSL-GST-NOTCH4
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C..TGGGAAC E.S. 0.496
GTTCCCA..G E.S. 0.496
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGAVN
NBTCHCABNN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH4 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-NOTCH4 Datasets
Complex Name Save View
MAML1-CSL-GST-NOTCH4 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH4 AMADID # 015681 save view
Gene Clone Type Last Modified Save View
NOTCH4 Not full length 2016-03-24 N/A N/A
Insert Sequence
1    RREHGALWLP PGFTRRPRTQ SAPHRRRPPL GEDSIGLKAL KPKAEVDEDG
51   VVMCSGPEEG EEVGQAEETG PPSTCQLWSL SGGCGALPQA AMLTPPQESE
101  MEAPDLDTRG PDGVTPLMSA VCCGEVQSGT FQGAWL GCP EPWEPLLDGG
151  ACPQAHTVGT GETPLHLAAR FSRPTAARRL LEAGANPNQP DRAGRTPLHA
201  AVAADAREVC QLLLRSRQTA VDARTEDGTT PLMLAARLAV EDLVEELIAA
251  QADVGARDKW GKTALHWAAA VNNARAA RS LLQAGADKDA QDNREQTPLF
301  LAAREGAVEV AQLLLGLGAA RELRDQAGLA PADVAHQRNH WDLLTLLEGA
351  GPPEARHKAT PGREAGPFPR ARTVSVSVPP HGGGALPRCR TLSAGAGPRG
401  GGACLQARTW SVDLAARG G GAYSHCRSLS GVGA



References
Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010


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