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                | -Genomic Data for MAML1 | Links |  
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                    ProteinMAML1 | 
                    UniPROBE Accession NumberUP00485 | 
                    SpeciesHomo sapiens | 
                    DomainNone Available | 
                    Swiss-ProtQ92585 |  
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                    Name and SynonymsName: mastermind-like 1 (Drosophila).
                    Synonyms:MAML 1; MAML-1; Mam1; Mam-1; FLJ53540; KIAA0200
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                    IHOP94966 |  
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                    NCBI RefSeqNP_055572.1 |  
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                                        	DescriptionActs as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation | 
                    JASPAR
                                                    None Available
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                | -PBM Motif Data for GST-NOTCH1_CSL-6His_MAML1 |  
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                            PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
                
              | 
                            PWMSave |  
                | 
                            Top Kmer
                CGTGGGAA    E.S. 0.497 TTCCCACG    E.S. 0.497 |  
                    | 
                                PBM-Derived DNA Binding Site Motif (BEEML-PBM)
                
              | 
                                PWMSave |  
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                                Consensus
                NNVTGDGARN NYTCHCABNN |  
                | 
                        Downloads
                            Download the zip 
                            of all GST-NOTCH1_CSL-6His_MAML1 PBM files 
                            or view the downloads directory 
                            for individual files.  
                            Please note that the files which include probe sequence data are protected by an academic research use license, 
                            which can be viewed here.
                         |  
        
            
                | -PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig5 |  
                | 
                            PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
                
              | 
                            PWMSave |  
                | 
                            Top Kmer
                C.TGGGAA.C    E.S. 0.493 G.TTCCCA.G    E.S. 0.493 |  
                    | 
                                PBM-Derived DNA Binding Site Motif (BEEML-PBM)
                
              | 
                                PWMSave |  
                    | 
                                Consensus
                NBVTGRGAAH DTTCYCABVN |  
                | 
                        Downloads
                            Download the zip 
                            of all MAML1-CSL-GST-NOTCH1_Fig5 PBM files 
                            or view the downloads directory 
                            for individual files.  
                            Please note that the files which include probe sequence data are protected by an academic research use license, 
                            which can be viewed here.
                         |  
        
            
                | -PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig2 |  
                | 
                            PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
                
              | 
                            PWMSave |  
                | 
                            Top Kmer
                C.TGGGAAC    E.S. 0.498 GTTCCCA.G    E.S. 0.498 |  
                    | 
                                PBM-Derived DNA Binding Site Motif (BEEML-PBM)
                
              | 
                                PWMSave |  
                    | 
                                Consensus
                NNTGDGAVNN NNBTCHCANN |  
                | 
                        Downloads
                            Download the zip 
                            of all MAML1-CSL-GST-NOTCH1_Fig2 PBM files 
                            or view the downloads directory 
                            for individual files.  
                            Please note that the files which include probe sequence data are protected by an academic research use license, 
                            which can be viewed here.
                         |  
        
            
                | -PBM Motif Data for MAML1-CSL-GST-NOTCH2_FigS1 |  
                | 
                            PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
                
              | 
                            PWMSave |  
                | 
                            Top Kmer
                C..TGGGAAC    E.S. 0.495 GTTCCCA..G    E.S. 0.495 |  
                    | 
                                PBM-Derived DNA Binding Site Motif (BEEML-PBM)
                
              | 
                                PWMSave |  
                    | 
                                Consensus
                NNVTGDGARN NYTCHCABNN |  
                | 
                        Downloads
                            Download the zip 
                            of all MAML1-CSL-GST-NOTCH2_FigS1 PBM files 
                            or view the downloads directory 
                            for individual files.  
                            Please note that the files which include probe sequence data are protected by an academic research use license, 
                            which can be viewed here.
                         |  
        
            
                | -PBM Motif Data for MAML1-CSL-GST-NOTCH2_Fig5 |  
                | 
                            PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
                
              | 
                            PWMSave |  
                | 
                            Top Kmer
                CC.TGGGAA    E.S. 0.492 TTCCCA.GG    E.S. 0.492 |  
                    | 
                                PBM-Derived DNA Binding Site Motif (BEEML-PBM)
                
              | 
                                PWMSave |  
                    | 
                                Consensus
                NBVTGRGAAH DTTCYCABVN |  
                | 
                        Downloads
                            Download the zip 
                            of all MAML1-CSL-GST-NOTCH2_Fig5 PBM files 
                            or view the downloads directory 
                            for individual files.  
                            Please note that the files which include probe sequence data are protected by an academic research use license, 
                            which can be viewed here.
                         |  
        
            
                | -PBM Motif Data for MAML1-CSL-GST-NOTCH3 |  
                | 
                            PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
                
              | 
                            PWMSave |  
                | 
                            Top Kmer
                CC.TGGGAA    E.S. 0.494 TTCCCA.GG    E.S. 0.494 |  
                    | 
                                PBM-Derived DNA Binding Site Motif (BEEML-PBM)
                
              | 
                                PWMSave |  
                    | 
                                Consensus
                NBVTGRGAAH DTTCYCABVN |  
                | 
                        Downloads
                            Download the zip 
                            of all MAML1-CSL-GST-NOTCH3 PBM files 
                            or view the downloads directory 
                            for individual files.  
                            Please note that the files which include probe sequence data are protected by an academic research use license, 
                            which can be viewed here.
                         |  
        
            
                | -PBM Motif Data for MAML1-CSL-GST-NOTCH4 |  
                | 
                            PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
                
              | 
                            PWMSave |  
                | 
                            Top Kmer
                C..TGGGAAC    E.S. 0.496 GTTCCCA..G    E.S. 0.496 |  
                    | 
                                PBM-Derived DNA Binding Site Motif (BEEML-PBM)
                
              | 
                                PWMSave |  
                    | 
                                Consensus
                NNVTGDGAVN NBTCHCABNN |  
                | 
                        Downloads
                            Download the zip 
                            of all MAML1-CSL-GST-NOTCH4 PBM files 
                            or view the downloads directory 
                            for individual files.  
                            Please note that the files which include probe sequence data are protected by an academic research use license, 
                            which can be viewed here.
                         |  
                            
                                
                                    | -MAML1 Datasets |  
                                            | Complex Name | Save | View |  
                                            | GST-NOTCH1_CSL-6His_MAML1 |   |   |  
                                            | Run name | PBM version | Save | View |  
                                                | GST-NOTCH1_CSL-6His_MAML1 | AMADID # 015681 |   |   |  
                                            | Complex Name | Save | View |  
                                            | MAML1-CSL-GST-NOTCH1 |   |   |  
                                            | Run name | PBM version | Save | View |  
                                                | MAML1-CSL-GST-NOTCH1_Fig5 | AMADID # 015681 |   |   |  
                                                | MAML1-CSL-GST-NOTCH1_Fig2 | AMADID # 015681 |   |   |  
                                            | Complex Name | Save | View |  
                                            | MAML1-CSL-GST-NOTCH2 |   |   |  
                                            | Run name | PBM version | Save | View |  
                                                | MAML1-CSL-GST-NOTCH2_FigS1 | AMADID # 015681 |   |   |  
                                                | MAML1-CSL-GST-NOTCH2_Fig5 | AMADID # 015681 |   |   |  
                                            | Complex Name | Save | View |  
                                            | MAML1-CSL-GST-NOTCH3 |   |   |  
                                            | Run name | PBM version | Save | View |  
                                                | MAML1-CSL-GST-NOTCH3 | AMADID # 015681 |   |   |  
                                            | Complex Name | Save | View |  
                                            | MAML1-CSL-GST-NOTCH4 |   |   |  
                                            | Run name | PBM version | Save | View |  
                                                | MAML1-CSL-GST-NOTCH4 | AMADID # 015681 |   |   |  
                                    | Gene | Clone Type | Last Modified | Save | View |  
        | MAML1 | Not full length | 2016-03-24 | N/A | N/A |  
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                Insert Sequence
                    1   LPRHSAVMER LRRRIELCRR HHSTCEARYE AVSPERLELE RQHTFALHQR 51  CIQAKAKRAG KH
 
 
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                References
                    Data are analyzed  by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010
                    
 
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