-Genomic Data for MAML1 Links
Protein
MAML1
UniPROBE Accession Number
UP00485
Species
Homo sapiens
Domain
None Available
Name and Synonyms
Name: mastermind-like 1 (Drosophila).
Synonyms:MAML 1; MAML-1; Mam1; Mam-1; FLJ53540; KIAA0200
Description
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation
-PBM Motif Data for GST-NOTCH1_CSL-6His_MAML1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CGTGGGAA E.S. 0.497
TTCCCACG E.S. 0.497
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGARN
NYTCHCABNN
Downloads
Download the zip of all GST-NOTCH1_CSL-6His_MAML1 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig5
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C.TGGGAA.C E.S. 0.493
G.TTCCCA.G E.S. 0.493
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NBVTGRGAAH
DTTCYCABVN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH1_Fig5 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C.TGGGAAC E.S. 0.498
GTTCCCA.G E.S. 0.498
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNTGDGAVNN
NNBTCHCANN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH1_Fig2 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH2_FigS1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C..TGGGAAC E.S. 0.495
GTTCCCA..G E.S. 0.495
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGARN
NYTCHCABNN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH2_FigS1 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH2_Fig5
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CC.TGGGAA E.S. 0.492
TTCCCA.GG E.S. 0.492
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NBVTGRGAAH
DTTCYCABVN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH2_Fig5 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH3
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CC.TGGGAA E.S. 0.494
TTCCCA.GG E.S. 0.494
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NBVTGRGAAH
DTTCYCABVN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH3 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for MAML1-CSL-GST-NOTCH4
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
C..TGGGAAC E.S. 0.496
GTTCCCA..G E.S. 0.496
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NNVTGDGAVN
NBTCHCABNN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH4 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-MAML1 Datasets
Complex Name Save View
GST-NOTCH1_CSL-6His_MAML1 save view
Run name PBM version Save View
GST-NOTCH1_CSL-6His_MAML1 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH1 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH1_Fig5 AMADID # 015681 save view
MAML1-CSL-GST-NOTCH1_Fig2 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH2 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH2_FigS1 AMADID # 015681 save view
MAML1-CSL-GST-NOTCH2_Fig5 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH3 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH3 AMADID # 015681 save view
Complex Name Save View
MAML1-CSL-GST-NOTCH4 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH4 AMADID # 015681 save view
Gene Clone Type Last Modified Save View
MAML1 Not full length 2016-03-24 N/A N/A
Insert Sequence
1   LPRHSAVMER LRRRIELCRR HHSTCEARYE AVSPERLELE RQHTFALHQR
51  CIQAKAKRAG KH



References
Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010


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