-Genomic Data for HESX1 Links
Protein
HESX1
UniPROBE Accession Number
UP00594
Species
Homo sapiens
Domain
Homeobox
Swiss-Prot
Q9UBX0
Name and Synonyms
Name: homeobox expressed in ES cells 1.
Synonyms:ANF, CPHD5, hAnf, HANF, Homeobox expressed in ES cells 1, Homeobox protein ANF, MGC138294, RPX
IHOP
94172
NCBI RefSeq
NP_003856
Description
Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation (By similarity).
JASPAR
None Available
-PBM Motif Data for HESX1_REF_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
CTAATTAG E.S. 0.499
CTAATTAG E.S. 0.499
Downloads
Download the zip of all HESX1_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HESX1_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
TTAATTAA E.S. 0.499
TTAATTAA E.S. 0.499
Downloads
Download the zip of all HESX1_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HESX1_E149K_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CTAATTAG E.S. 0.499
CTAATTAG E.S. 0.499
Downloads
Download the zip of all HESX1_E149K PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HESX1_N125S_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
TTAATTAA E.S. 0.499
TTAATTAA E.S. 0.499
Downloads
Download the zip of all HESX1_N125S PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HESX1_N125S_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
G.TAATTA.C E.S. 0.499
G.TAATTA.C E.S. 0.499
Downloads
Download the zip of all HESX1_N125S PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HESX1_R160C_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
GA.A.AAAAA E.S. 0.416
TTTTT.T.TC E.S. 0.416
Downloads
Download the zip of all HESX1_R160C PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for HESX1 (all alleles)
Downloads
Download the zip of all HESX1 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-HESX1 Datasets
Clone Clone Type Last Modified Save View
HESX1_REF DNA binding domain only search save
HESX1_REF Insert Sequence
1   ERLSLKRELS WYRGRRPRTA FTQNQIEVLE NVFRVNCYPG IDIREDLAQK
51  LNLEEDRIQI WFQNRRAKLK RSHRESQFLM AKKNFN


HESX1_E149K DNA binding domain only search save
HESX1_E149K Insert Sequence
1   ERLSLKRELS WYRGRRPRTA FTQNQIEVLE NVFRVNCYPG IDIREDLAQK
51  LNLEKDRIQI WFQNRRAKLK RSHRESQFLM AKKNFN


HESX1_N125S DNA binding domain only search save
HESX1_N125S Insert Sequence
1   ERLSLKRELS WYRGRRPRTA FTQNQIEVLE SVFRVNCYPG IDIREDLAQK
51  LNLEEDRIQI WFQNRRAKLK RSHRESQFLM AKKNFN


HESX1_R160C DNA binding domain only search save
HESX1_R160C Insert Sequence
1   ERLSLKRELS WYRGRRPRTA FTQNQIEVLE NVFRVNCYPG IDIREDLAQK
51  LNLEEDRIQI WFQNRCAKLK RSHRESQFLM AKKNFN


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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