-Genomic Data for PAX7 Links
Protein
PAX7
UniPROBE Accession Number
UP00612
Species
Homo sapiens
Domain
PAX
Name and Synonyms
Name: paired box protein Pax-7.
Synonyms:FLJ37460, Hup1, HuP1, HUP1, Paired box protein Pax-7, PAX7B, RMS2
Description
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
PAX7 DNA binding domain
1   RRSRTTFTAE QLEELEKAFE RTHYPDIYTR EELAQRTKLT EARVQVWFSN
51  RRARWRK
-PBM Motif Data for PAX7_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
ACCGTGAC E.S. 0.499
GTCACGGT E.S. 0.499
Downloads
Download the zip of all PAX7_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX7_P112L_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available.  We apologize for the inconvenience.
PWM
Save
Top Kmer
ACCGTGAC E.S. 0.499
GTCACGGT E.S. 0.499
Downloads
Download the zip of all PAX7_P112L PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for PAX7 (all alleles)
Downloads
Download the zip of all PAX7 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PAX7 Datasets
Clone Clone Type Last Modified Save View
PAX7_REF DNA binding domain only search save
PAX7_REF Insert Sequence
1    YPRTGFPLEV STPLGQGRVN QLGGVFINGR PLPNHIRHKI VEMAHHGIRP
51   CVISRQLRVS HGCVSKILCR YQETGSIRPG AIGGSKPRQV ATPDVEKKIE
101  EYKRENPGMF SWEIRDRLLK DGHCDRSTVP SVSSISRVLR IKFGKKEEED
151  EADKK



PAX7_P112L DNA binding domain only search save
PAX7_P112L Insert Sequence
1    YPRTGFPLEV STPLGQGRVN QLGGVFINGR PLPNHIRHKI VEMAHHGIRP
51   CVISRQLRVS HGCVSKILCR YQETGSIRPG AIGGSKPRQV ATLDVEKKIE
101  EYKRENPGMF SWEIRDRLLK DGHCDRSTVP SVSSISRVLR IKFGKKEEED
151  EADKK



References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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