-Genomic Data for VAX2 Links
Protein
VAX2
UniPROBE Accession Number
UP00623
Species
Homo sapiens
Domain
Homeobox
Swiss-Prot
Q9UIW0
Name and Synonyms
Name: ventral anterior homeobox 2.
Synonyms:DRES93, Ventral anterior homeobox 2
IHOP
97186
Description
Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists including the expression of a truncated TCF7L2 isoform that cannot bind CTNNB1 and acts therefore as a potent dominant-negative Wnt antagonist. Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity). May be a regulator of axial polarization in the retina.
NCBI RefSeq
NP_036608
VAX2 DNA binding domain
1   KRTRTSFTAE QLYRLEMEFQ RCQYVVGRER TELARQLNLS ETQVKVWFQN
51  RRTKQKK
JASPAR
None Available
-PBM Motif Data for VAX2_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
G.TAATTA.C E.S. 0.498
G.TAATTA.C E.S. 0.498
Downloads
Download the zip of all VAX2_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for VAX2_REF_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
G.TAATTA.C E.S. 0.498
G.TAATTA.C E.S. 0.498
Downloads
Download the zip of all VAX2_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for VAX2_L139M_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
G.TAATTA.C E.S. 0.498
G.TAATTA.C E.S. 0.498
Downloads
Download the zip of all VAX2_L139M PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for VAX2_L139M_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
G.TAATTA.C E.S. 0.498
G.TAATTA.C E.S. 0.498
Downloads
Download the zip of all VAX2_L139M PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for VAX2 (all alleles)
Downloads
Download the zip of all VAX2 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-VAX2 Datasets
Clone Clone Type Last Modified Save View
VAX2_REF DNA binding domain only search save
VAX2_REF Insert Sequence
1   TIREIVLPKG LDLDRPKRTR TSFTAEQLYR LEMEFQRCQY VVGRERTELA
51  RQLNLSETQV KVWFQNRRTK QKKDQSRDLE KRASSSASEA


VAX2_L139M DNA binding domain only search save
VAX2_L139M Insert Sequence
1   TIREIVLPKG LDLDRPKRTR TSFTAEQLYR LEMEFQRCQY VVGRERTELA
51  RQMNLSETQV KVWFQNRRTK QKKDQSRDLE KRASSSASEA


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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