-Genomic Data Links
Protein
Irx3
UniPROBE Accession Number
UP00223
Species
Mus musculus
Domain
Homeobox
Name and Synonyms
Iroquois related homeobox 3 (Drosophila)
Homeodomain protein IRXB1, Iroquois-class homeodomain protein IRX-3, Iroquois homeobox protein 3, Irxb1
Description
None Available
Irx3 DNA binding domain
1   PKNATRESTS TLKAWLNEHR KNPYPTKGEK IMLAIITKMT LTQVSTWFAN
51  ARRRLKK
-PBM Motif Data for Irx3
Primary Motif (clone pTH920 )  (Seed-and-Wobble)
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Primary PWM
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Top Kmer
TACATGTA (E.S. 0.49513)
TACATGTA (E.S. 0.49513)
Primary Motif (clone pTH920 )  (BEEML-PBM)
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Primary PWM
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Consensus
NNNDTGTHNN
NNDACAHNNN
Primary Motif (clone pTH2226 )  (Seed-and-Wobble)
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Primary PWM
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Top Kmer
TACATGTA (E.S. 0.49597)
TACATGTA (E.S. 0.49597)
Primary Motif (clone pTH2226 )  (BEEML-PBM)
Image Not Available.  We apologize for the inconvenience.
Primary PWM
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Consensus
NNDACWHNNN
NNNDWGTHNN
Downloads
Download the zip of all Irx3 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Link to TFBSshape
This link will take you to the corresponding entry for Irx3 in TFBSshape, a database which provides information about the shape of the DNA at transcription factor binding sites.

http://rohslab.cmb.usc.edu/TFBSshape/?tfid=&geneID=223&sourceDB=uniprobe

-Irx3 Datasets
Clone ID Expression Expression Method Save View
pTH920 #1 IVT save search
pTH2226 #1 IVT save search
Clone pTH920 insert sequence
1    PHPAFYPYGQ YQFGDPSRPK NATRESTSTL KAWLNEHRKN PYPTKGEKIM
51   LAIITKMTLT QVSTWFANAR RRLKKENKMT WAPRSRTDEE GNAYGSEREE
101  EDEEEDEEES KRELEMEEEG NAYG

References
Data are analyzed by array design with AMADID # 015681 in Berger et al., Cell 2008


Clone pTH2226 insert sequence
1    PHPAFYPYGQ YQFGDPSRPK NATRESTSTL KAWLNEHRKN PYPTKGEKIM
51   LAIITKMTLT QVSTWFANAR RRLKKENKMT WAPRSRTDEE GNAYGSEREE
101  EDEEEDEEES KRELEMEEEE LAGEEEDTGG EGLADDDEDE EIDLENLDSA
151  AAGSELTLAG AAHRNGDFGL GPISDCKTS

References
Data are analyzed by array design with AMADID # 015681 in Berger et al., Cell 2008


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