|
|
| -Genomic Data for NOTCH1 |
Links |
- Protein
- NOTCH1
|
- UniPROBE Accession Number
- UP00480
|
- Species
- Homo sapiens
|
- Domain
- None Available
|
- Swiss-Prot
- P46531
|
- Name and Synonyms
- Name: notch 1.
Synonyms:hN1, Neurogenic locus notch homolog protein 1, NOTCH1, Notch 1, TAN1, Translocation-associated notch protein TAN-1
|
- IHOP
- 90627
|
- NCBI RefSeq
- NP_060087.3
|
- Description
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptot
|
- JASPAR
-
None Available
|
| -PBM Motif Data for GST-CSL-NOTCH1 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
CGTGGGAA E.S. 0.498
TTCCCACG E.S. 0.498
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
NNVTGDGAVN
NBTCHCABNN
|
- Downloads
-
Download the zip
of all GST-CSL-NOTCH1 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -PBM Motif Data for GST-NOTCH1_Fig2 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
A.TGGGAAA E.S. 0.479
TTTCCCA.T E.S. 0.479
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
NNTGRGARNN
NNYTCYCANN
|
- Downloads
-
Download the zip
of all GST-NOTCH1_Fig2 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -PBM Motif Data for GST-NOTCH1_Fig4 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
AATAAAA..A E.S. 0.445
T..TTTTATT E.S. 0.445
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
DNWNDDRRRA
TYYYHHNWNH
|
- Downloads
-
Download the zip
of all GST-NOTCH1_Fig4 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -PBM Motif Data for GST-NOTCH1_CSL-6His |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
C.TGGGAAC E.S. 0.495
GTTCCCA.G E.S. 0.495
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
NNVTGDGARN
NYTCHCABNN
|
- Downloads
-
Download the zip
of all GST-NOTCH1_CSL-6His PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -PBM Motif Data for GST-NOTCH1_CSL-6His_MAML1 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
CGTGGGAA E.S. 0.497
TTCCCACG E.S. 0.497
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
NNVTGDGARN
NYTCHCABNN
|
- Downloads
-
Download the zip
of all GST-NOTCH1_CSL-6His_MAML1 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig5 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
C.TGGGAA.C E.S. 0.493
G.TTCCCA.G E.S. 0.493
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
NBVTGRGAAH
DTTCYCABVN
|
- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH1_Fig5 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig2 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
C.TGGGAAC E.S. 0.498
GTTCCCA.G E.S. 0.498
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
NNTGDGAVNN
NNBTCHCANN
|
- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH1_Fig2 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -NOTCH1 Datasets |
| Complex Name |
Save |
View |
| GST-CSL-NOTCH1 |
|
|
| Run name |
PBM version |
Save |
View |
| GST-CSL-NOTCH1 | AMADID # 015681 |
|
|
| Complex Name |
Save |
View |
| GST-NOTCH1 |
|
|
| Run name |
PBM version |
Save |
View |
| GST-NOTCH1_Fig2 | AMADID # 015681 |
|
|
| GST-NOTCH1_Fig4 | AMADID # 015681 |
|
|
| Complex Name |
Save |
View |
| GST-NOTCH1_CSL-6His |
|
|
| Run name |
PBM version |
Save |
View |
| GST-NOTCH1_CSL-6His | AMADID # 015681 |
|
|
| Complex Name |
Save |
View |
| GST-NOTCH1_CSL-6His_MAML1 |
|
|
| Run name |
PBM version |
Save |
View |
| GST-NOTCH1_CSL-6His_MAML1 | AMADID # 015681 |
|
|
| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH1 |
|
|
| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH1_Fig5 | AMADID # 015681 |
|
|
| MAML1-CSL-GST-NOTCH1_Fig2 | AMADID # 015681 |
|
|
| Gene |
Clone Type |
Last Modified |
Save |
View |
| NOTCH1 |
Not full length |
2014-08-13 |
N/A
|
N/A
|
- Insert Sequence
-
1 RRQHGQLWFP EGFKVSEASK KKRREPLGED SVGLKPLKNA SDGALMDDNQ
51 NEWGDEDLET KKFRFEEPVV LPDLDDQTDH RQWTQQHLDA ADLRMSAMAP
101 TPPQGEVDAD CMDVNVRGPD GFTPLMIASC SGGGLETGNS EEEEDAPAVI
151 SDFIYQGASL HNQTDRTGET ALHLAARYSR SDAAKRLLEA SADANIQDNM
201 GRTPLHAAVS ADAQGVFQIL IRNRATDLDA RMHDGTTPLI LAARLAVEGM
251 LEDLINSHAD VNAVDDLGKS ALHWAAAVNN VDAAVVLLKN GANKDMQNNR
301 EETPLFLAAR EGSYETAKVL LDHFANRDIT DHMDRLPRDI AQERMHHDIV
351 RLLDEYNLVR SPQLHGA
|
- References
-
Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010
|
|