-Genomic Data for NOTCH3 Links
Protein
NOTCH3
UniPROBE Accession Number
UP00482
Species
Homo sapiens
Domain
None Available
Name and Synonyms
Name: notch 3.
Synonyms:IMF2; CASIL; CADASIL
Description
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptot
-PBM Motif Data for MAML1-CSL-GST-NOTCH3
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CC.TGGGAA E.S. 0.494
TTCCCA.GG E.S. 0.494
PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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PWM
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Consensus
NBVTGRGAAH
DTTCYCABVN
Downloads
Download the zip of all MAML1-CSL-GST-NOTCH3 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-NOTCH3 Datasets
Complex Name Save View
MAML1-CSL-GST-NOTCH3 save view
Run name PBM version Save View
MAML1-CSL-GST-NOTCH3 AMADID # 015681 save view
Gene Clone Type Last Modified Save View
NOTCH3 Not full length 2014-08-13 N/A N/A
Insert Sequence
1    KREHSTLWFP EGFSLHKDVA SGHKGRREPV GQDALGMKNM AKGESLMGEV
51   ATDWMDTECP EAKRLKVEEP GMGAEEAVDC RQWTQHHLVA ADIRVAPAMA
101  LTPPQGDADA DGMDVNVRGP DGFTPLMLAS FCGGALEPMP TEEDEADDTS
151  ASIISDLICQ GAQLGARTDR TGETALHLAA RYARADAAKR LLDAGADTNA
201  QDHSGRTPLH TAVTADAQGV FQILIRNRST DLDARMADGS TALILAARLA
251  VEGMVEELIA SHADVNAVDE LGKSALHWAA AVNNVEATLA LLKNGANKDM
301  QDSKEETPLF LAAREGSYEA AKLLLDHFAN REITDHLDRL PRDVAQERLH
351  QDIVRLLDQP SGPRSPPGPH GL



References
Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010


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