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| -Genomic Data for NOTCH3 |
Links |
- Protein
- NOTCH3
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- UniPROBE Accession Number
- UP00482
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- Species
- Homo sapiens
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- Domain
- None Available
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- Swiss-Prot
- Q9UM47
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- Name and Synonyms
- Name: notch 3.
Synonyms:IMF2; CASIL; CADASIL
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- IHOP
- 90630
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- NCBI RefSeq
- NP_000426.2
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- Description
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptot
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- JASPAR
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None Available
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH3 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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CC.TGGGAA E.S. 0.494
TTCCCA.GG E.S. 0.494
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NBVTGRGAAH
DTTCYCABVN
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- Downloads
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Download the zip
of all MAML1-CSL-GST-NOTCH3 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -NOTCH3 Datasets |
| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH3 |
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| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH3 | AMADID # 015681 |
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| Gene |
Clone Type |
Last Modified |
Save |
View |
| NOTCH3 |
Not full length |
2014-08-13 |
N/A
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N/A
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- Insert Sequence
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1 KREHSTLWFP EGFSLHKDVA SGHKGRREPV GQDALGMKNM AKGESLMGEV
51 ATDWMDTECP EAKRLKVEEP GMGAEEAVDC RQWTQHHLVA ADIRVAPAMA
101 LTPPQGDADA DGMDVNVRGP DGFTPLMLAS FCGGALEPMP TEEDEADDTS
151 ASIISDLICQ GAQLGARTDR TGETALHLAA RYARADAAKR LLDAGADTNA
201 QDHSGRTPLH TAVTADAQGV FQILIRNRST DLDARMADGS TALILAARLA
251 VEGMVEELIA SHADVNAVDE LGKSALHWAA AVNNVEATLA LLKNGANKDM
301 QDSKEETPLF LAAREGSYEA AKLLLDHFAN REITDHLDRL PRDVAQERLH
351 QDIVRLLDQP SGPRSPPGPH GL
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- References
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Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010
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