|
|
| -Genomic Data for NOTCH4 |
Links |
- Protein
- NOTCH4
|
- UniPROBE Accession Number
- UP00483
|
- Species
- Homo sapiens
|
- Domain
- None Available
|
- Swiss-Prot
- Q99466
|
- Name and Synonyms
- Name: notch 4.
Synonyms:INT3; FLJ16302; MGC74442
|
- IHOP
- 90631
|
- NCBI RefSeq
- NP_004548.3
|
- Description
- Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptot
|
- JASPAR
-
None Available
|
| -PBM Motif Data for MAML1-CSL-GST-NOTCH4 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
-
|
- PWM
- Save
|
- Top Kmer
-
C..TGGGAAC E.S. 0.496
GTTCCCA..G E.S. 0.496
|
- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
-
|
- PWM
- Save
|
- Consensus
-
NNVTGDGAVN
NBTCHCABNN
|
- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH4 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
|
| -NOTCH4 Datasets |
| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH4 |
|
|
| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH4 | AMADID # 015681 |
|
|
| Gene |
Clone Type |
Last Modified |
Save |
View |
| NOTCH4 |
Not full length |
2014-08-13 |
N/A
|
N/A
|
- Insert Sequence
-
1 RREHGALWLP PGFTRRPRTQ SAPHRRRPPL GEDSIGLKAL KPKAEVDEDG
51 VVMCSGPEEG EEVGQAEETG PPSTCQLWSL SGGCGALPQA AMLTPPQESE
101 MEAPDLDTRG PDGVTPLMSA VCCGEVQSGT FQGAWL GCP EPWEPLLDGG
151 ACPQAHTVGT GETPLHLAAR FSRPTAARRL LEAGANPNQP DRAGRTPLHA
201 AVAADAREVC QLLLRSRQTA VDARTEDGTT PLMLAARLAV EDLVEELIAA
251 QADVGARDKW GKTALHWAAA VNNARAA RS LLQAGADKDA QDNREQTPLF
301 LAAREGAVEV AQLLLGLGAA RELRDQAGLA PADVAHQRNH WDLLTLLEGA
351 GPPEARHKAT PGREAGPFPR ARTVSVSVPP HGGGALPRCR TLSAGAGPRG
401 GGACLQARTW SVDLAARG G GAYSHCRSLS GVGA
|
- References
-
Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010
|
|