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| -Genomic Data for MAML1 |
Links |
- Protein
- MAML1
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- UniPROBE Accession Number
- UP00485
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- Species
- Homo sapiens
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- Domain
- None Available
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- Swiss-Prot
- Q92585
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- Name and Synonyms
- Name: mastermind-like 1 (Drosophila).
Synonyms:MAML 1; MAML-1; Mam1; Mam-1; FLJ53540; KIAA0200
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- IHOP
- 94966
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- NCBI RefSeq
- NP_055572.1
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- Description
- Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation
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- JASPAR
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None Available
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| -PBM Motif Data for GST-NOTCH1_CSL-6His_MAML1 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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CGTGGGAA E.S. 0.497
TTCCCACG E.S. 0.497
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NNVTGDGARN
NYTCHCABNN
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- Downloads
-
Download the zip
of all GST-NOTCH1_CSL-6His_MAML1 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig5 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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C.TGGGAA.C E.S. 0.493
G.TTCCCA.G E.S. 0.493
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NBVTGRGAAH
DTTCYCABVN
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- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH1_Fig5 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH1_Fig2 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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C.TGGGAAC E.S. 0.498
GTTCCCA.G E.S. 0.498
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NNTGDGAVNN
NNBTCHCANN
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- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH1_Fig2 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH2_FigS1 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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C..TGGGAAC E.S. 0.495
GTTCCCA..G E.S. 0.495
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NNVTGDGARN
NYTCHCABNN
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- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH2_FigS1 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH2_Fig5 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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CC.TGGGAA E.S. 0.492
TTCCCA.GG E.S. 0.492
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NBVTGRGAAH
DTTCYCABVN
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- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH2_Fig5 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH3 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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CC.TGGGAA E.S. 0.494
TTCCCA.GG E.S. 0.494
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
-
NBVTGRGAAH
DTTCYCABVN
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- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH3 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -PBM Motif Data for MAML1-CSL-GST-NOTCH4 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- Save
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- Top Kmer
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C..TGGGAAC E.S. 0.496
GTTCCCA..G E.S. 0.496
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- PBM-Derived DNA Binding Site Motif (BEEML-PBM)
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- PWM
- Save
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- Consensus
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NNVTGDGAVN
NBTCHCABNN
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- Downloads
-
Download the zip
of all MAML1-CSL-GST-NOTCH4 PBM files
or view the downloads directory
for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -MAML1 Datasets |
| Complex Name |
Save |
View |
| GST-NOTCH1_CSL-6His_MAML1 |
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| Run name |
PBM version |
Save |
View |
| GST-NOTCH1_CSL-6His_MAML1 | AMADID # 015681 |
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| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH1 |
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| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH1_Fig5 | AMADID # 015681 |
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| MAML1-CSL-GST-NOTCH1_Fig2 | AMADID # 015681 |
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| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH2 |
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| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH2_FigS1 | AMADID # 015681 |
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| MAML1-CSL-GST-NOTCH2_Fig5 | AMADID # 015681 |
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| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH3 |
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| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH3 | AMADID # 015681 |
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| Complex Name |
Save |
View |
| MAML1-CSL-GST-NOTCH4 |
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| Run name |
PBM version |
Save |
View |
| MAML1-CSL-GST-NOTCH4 | AMADID # 015681 |
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| Gene |
Clone Type |
Last Modified |
Save |
View |
| MAML1 |
Not full length |
2014-08-13 |
N/A
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N/A
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- Insert Sequence
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1 LPRHSAVMER LRRRIELCRR HHSTCEARYE AVSPERLELE RQHTFALHQR
51 CIQAKAKRAG KH
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- References
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Data are analyzed by array design with AMADID # 015681 in Del Bianco et al., PLoS ONE 2010
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