-Genomic Data for Gli1 Links
Protein
Gli1
UniPROBE Accession Number
UP00538
Species
Mus musculus
Domain
zf-H2C2_2
Name and Synonyms
Name: GLI-Kruppel family member GLI1.
Synonyms:Zinc finger protein GLI1; AV235269; Zfp-5; Zfp5; Glioma-associated oncogene homolog
Description
Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
-PBM Motif Data for Gli1
Primary Motif
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Primary PWM
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Top Kmer
GACCACCC E.S. 0.498
GGGTGGTC E.S. 0.498
Secondary Motif
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Secondary PWM
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Top Kmer
ACC.CCCAC E.S. 0.491
GTGGG.GGT E.S. 0.491
Primary Motif
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Primary PWM
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Top Kmer
GACCACCC E.S. 0.498
GGGTGGTC E.S. 0.498
Secondary Motif
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Secondary PWM
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Top Kmer
ACC.CCCAC E.S. 0.492
GTGGG.GGT E.S. 0.492
PBM-Derived DNA Binding Site Motif (BEEML-PBM) (AMADID # 015681)
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PWM
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Consensus
NKVCCHCMNN
NNKGDGGBMN
PBM-Derived DNA Binding Site Motif (BEEML-PBM) (AMADID # 016060)
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PWM
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Consensus
KVCCNCMNNN
NNNKGNGGBM
Downloads
Download the zip of all Gli1 PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-Gli1 Datasets
Gene Clone Type Last Modified Save View
Gli1 DNA binding domain only 2014-09-06 search save
Gli1 Insert Sequence
1    DLEREEKPEP ESVYETDCRW DGCSQEFDSQ EQLVHHINSE HIHGERKEFV
51   CHWGGCSREL RPFKAQYMLV VHMRRHTGEK PHKCTFEGCR KSYSRLENLK
101  THLRSHTGEK PYMCEQEGCS KAFSNASDRA KHQNRTHSNE KPYVCKLPGC
151  TKRYTDPSSL RKHVKTVHGP DAHVTKRHRG DGPLPRAQ



References
Data are analyzed by array designs with AMADID #s 016060, 015681 in Peterson et al., Genes Dev 2012


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