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| -Genomic Data for CND-1 |
Links |
- Gene
- cnd-1
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- Species
- $species
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- Domain
- bHLH
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- IHOP
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48002
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- Swiss-Prot
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P46581
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- UniPROBE Accession Number
- $accession_id
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- Synonyms
- hlh-5
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- $refseq_designator
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NP_498115
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- Wormbase Protein ID
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WP:CE01187
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- EdgeDB Promoter
- Pcnd-1
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- Wormbase Gene ID
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WBGene00000561
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- Description (from Wormbase)
- cnd-1 encodes a basic helix-loop-helix protein that is most closely related to the vertebrate NeuroD transcription factors; during development, CND-1 is predicted to function as a transcriptional regulator whose activity is required for several aspects of motor neuron fate specification, including cell division patterns, proper spatiotemporal expression of fate-specific markers, and normal axonal morphology and pathfinding; CND-1::GFP expression begins in early embryogenesis (<20 cells) in four AB descendants and then continues in mitotically active AB-derived neuronal precursors, unidentified nuclei during gastrulation and enclosure, and postmitotic neurons in the head and ventral cord; at hatching CND-1::GFP expression is visible in ventral cord neurons, but this expression disappears completely by the end of the first larval stage; CND-1::GFP does not appear to be expressed in any non-neuronal ectodermal cells, as its expression does not overlap with that of LIN-26.
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| -PBM Motif Data for CND-1 |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
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View
Save
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- Top Kmer
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AAAAAAAA E.S. 0.428
TTTTTTTT E.S. 0.428
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- Downloads
-
Download the
zip
of all CND-1 PBM files
or view the
downloads directory
for individual files.
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| -PBM Motif Data for HLH-2/CND-1 Heterodimer |
- PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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- PWM
- View
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- Top Kmer
-
AACA.CTGT E.S. 0.480
ACAG.TGTT E.S. 0.480
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- Downloads
- Download the zip of all HLH-2/CND-1 interaction files or view the downloads directory for individual files.
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| -CND-1 Datasets |
| Gene |
Homodimerizes |
Clone Type |
Last Modified |
Save |
View |
|
cnd-1
|
No |
Full length clone |
2014-07-16 |
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- CND-1 Insert Sequence
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1 RPTDTSNFAP AEISKRKVRR VKANGRERAR MHGLNNALDM LREYIPITTQ
51 HQKLSKIETL RLARNYIDAL QRMLQTNEQP TPLEYAHTLA NGLSQTTTNM
101 LANLLQVQPR QLLPPSQFDI FSDPSHHQLH PSHPPPHSSF SSSSPSSSCS
151 PPQYYYSPTQ PSAAPLQGSC DPQYQQMYHQ HSHQNTFNYS P
- Mutations away from WormBase CND-1 wildtype:
- • Methioinine start not included in insert sequence
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| CND-1 Interacts With |
Clone Type |
Last Modified |
Save |
View |
| HLH-2 |
Full length clone |
2008-07-23 |
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