-Genomic Data for HLH-26 Links
Gene
hlh-26
Species
$species
Domain
bHLH
UniPROBE Accession Number
$accession_id
Synonyms
None Available
Description (from Wormbase)
hlh-26 encodes a REF-1-like protein with two bHLH domains that represses lag-2 transcription in ABa descendants (in response to a Notch signal, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28) and tbx-37 transcription in EMS descendants (independently of Notch, redundantly with REF-1, HLH-27, HLH-29, and perhaps HLH-28); lag-2 repression by HLH-26 may require UNC-37; HLH-26's paralogs include HLH-25 through HLH-29 and (more distantly) REF-1; HLH-26 is not visibly expressed in EMS descendants, and has no obvious function in mass RNAi assays.
-PBM Motif Data for HLH-26
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CACGTGTC E.S. 0.491
GACACGTG E.S. 0.491
Downloads
Download the zip of all HLH-26 PBM files or view the downloads directory for individual files.
-HLH-26 Datasets
Gene Homodimerizes Clone Type Last Modified Save View
hlh-26 Yes Full length clone 2014-07-16 search save
HLH-26 Insert Sequence
1    SSSPTSSSSG SPSSHGHRSE TEKQRRDDTN DLLNEFKKIV QKSESEKLSK
51   EEVLFRIVKL LSGIQLHHES FSTSPGPIRS IKKIKSDREQ VRRNKRVAAY
101  RELRKFIALN NLSSSEEIDK MENLKVLEII FEVIRGKSIT CTVPCLPFPI
151  LPFLPVFPVY SPLVFNSYNQ FSLYPPHMPT VQIPIVPSSS FEIDALEIEE
201  NEKDIDIVG


Mutations away from WormBase HLH-26 wildtype:
• Methioinine start not included in insert sequence

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