-Genomic Data for HOXB7 Links
Protein
HOXB7
UniPROBE Accession Number
UP00595
Species
Homo sapiens
Domain
Homeobox
Name and Synonyms
Name: homeobox protein Hox-B7.
Synonyms:HHO.C1, Homeobox protein HHO.C1, Homeobox protein Hox-2C, Homeobox protein Hox-B7, HOX2, Hox-2.3, HOX2C
Description
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.
HOXB7 DNA binding domain
1   KRGRQTYTRY QTLELEKEFH YNRYLTRRRR IEIAHTLCLT ERQIKIWFQN
51  RRMKWKK
-PBM Motif Data for HOXB7_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
GTAATTAC E.S. 0.484
GTAATTAC E.S. 0.484
Downloads
Download the zip of all HOXB7_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXB7_REF_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
ATAATTA..G E.S. 0.477
C..TAATTAT E.S. 0.477
Downloads
Download the zip of all HOXB7_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXB7_K191R_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
GTAATTAC E.S. 0.468
GTAATTAC E.S. 0.468
Downloads
Download the zip of all HOXB7_K191R PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXB7_K191R_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
TAAT..ATTA E.S. 0.475
TAAT..ATTA E.S. 0.475
Downloads
Download the zip of all HOXB7_K191R PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXB7_M190L_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
ATAATTA..G E.S. 0.467
C..TAATTAT E.S. 0.467
Downloads
Download the zip of all HOXB7_M190L PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXB7_M190L_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
AT.TATA.AT E.S. 0.459
AT.TATA.AT E.S. 0.459
Downloads
Download the zip of all HOXB7_M190L PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXB7_R189C_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
AT.TATA.AT E.S. 0.453
AT.TATA.AT E.S. 0.453
Downloads
Download the zip of all HOXB7_R189C PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for HOXB7 (all alleles)
Downloads
Download the zip of all HOXB7 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-HOXB7 Datasets
Clone Clone Type Last Modified Save View
HOXB7_REF DNA binding domain only search save
HOXB7_REF Insert Sequence
1   SNFRIYPWMR SSGTDRKRGR QTYTRYQTLE LEKEFHYNRY LTRRRRIEIA
51  HTLCLTERQI KIWFQNRRMK WKKENKTAGP GTTGQDRAEA



HOXB7_K191R DNA binding domain only search save
HOXB7_K191R Insert Sequence
1   SNFRIYPWMR SSGTDRKRGR QTYTRYQTLE LEKEFHYNRY LTRRRRIEIA
51  HTLCLTERQI KIWFQNRRMR WKKENKTAGP GTTGQDRAEA



HOXB7_M190L DNA binding domain only search save
HOXB7_M190L Insert Sequence
1   SNFRIYPWMR SSGTDRKRGR QTYTRYQTLE LEKEFHYNRY LTRRRRIEIA
51  HTLCLTERQI KIWFQNRRLK WKKENKTAGP GTTGQDRAEA



HOXB7_R189C DNA binding domain only search save
HOXB7_R189C Insert Sequence
1   SNFRIYPWMR SSGTDRKRGR QTYTRYQTLE LEKEFHYNRY LTRRRRIEIA
51  HTLCLTERQI KIWFQNRCMK WKKENKTAGP GTTGQDRAEA



References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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