-Genomic Data for HOXD13 Links
Protein
HOXD13
UniPROBE Accession Number
UP00597
Species
Homo sapiens
Domain
Homeobox
Swiss-Prot
P35453
Name and Synonyms
Name: homeobox protein Hox-D13.
Synonyms:BDE, BDSD, Homeobox protein Hox-4I, Homeobox protein Hox-D13, HOX4I, SPD
IHOP
89146
Description
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.
NCBI RefSeq
NP_000514
HOXD13 DNA binding domain
1   RKKRVPYTKL QLKELENEYA INKFINKDKR RRISAATNLS ERQVTIWFQN
51  RRVKDKK
JASPAR
None Available
-PBM Motif Data for HOXD13_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CTCGTAAA E.S. 0.496
TTTACGAG E.S. 0.496
Downloads
Download the zip of all HOXD13_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_REF_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CAATAAA E.S. 0.493
TTTTATTG E.S. 0.493
Downloads
Download the zip of all HOXD13_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_I297V_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CAATAAAA E.S. 0.495
TTTTATTG E.S. 0.495
Downloads
Download the zip of all HOXD13_I297V PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_I322L_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CTCGTAAA E.S. 0.498
TTTACGAG E.S. 0.498
Downloads
Download the zip of all HOXD13_I322L PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_I322L_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CTCGTAAA E.S. 0.499
TTTACGAG E.S. 0.499
Downloads
Download the zip of all HOXD13_I322L PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_N298S_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CAATAAAA E.S. 0.494
TTTTATTG E.S. 0.494
Downloads
Download the zip of all HOXD13_N298S PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_Q325K_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
GG.ATAAAA E.S. 0.495
TTTTAT.CC E.S. 0.495
Downloads
Download the zip of all HOXD13_Q325K PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_Q325R_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
GTATAAAA E.S. 0.495
TTTTATAC E.S. 0.495
Downloads
Download the zip of all HOXD13_Q325R PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_Q325R_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
GTATAAAA E.S. 0.497
TTTTATAC E.S. 0.497
Downloads
Download the zip of all HOXD13_Q325R PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_R306W_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CAATAAAA E.S. 0.499
TTTTATTG E.S. 0.499
Downloads
Download the zip of all HOXD13_R306W PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_R306W_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
CAATAAAA E.S. 0.498
TTTTATTG E.S. 0.498
Downloads
Download the zip of all HOXD13_R306W PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_S316C_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
CAATAAAA E.S. 0.497
TTTTATTG E.S. 0.497
Downloads
Download the zip of all HOXD13_S316C PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for HOXD13_S316C_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
CTCGTAAA E.S. 0.496
TTTACGAG E.S. 0.496
Downloads
Download the zip of all HOXD13_S316C PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for HOXD13 (all alleles)
Downloads
Download the zip of all HOXD13 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-HOXD13 Datasets
Clone Clone Type Last Modified Save View
HOXD13_REF DNA binding domain only search save
HOXD13_REF Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAINKFIN KDKRRRISAA
51  TNLSERQVTI WFQNRRVKDK KIVSKLKDTV S


HOXD13_I297V DNA binding domain only search save
HOXD13_I297V Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAVNKFIN KDKRRRISAA
51  TNLSERQVTI WFQNRRVKDK KIVSKLKDTV S


HOXD13_I322L DNA binding domain only search save
HOXD13_I322L Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAINKFIN KDKRRRISAA
51  TNLSERQVTL WFQNRRVKDK KIVSKLKDTV S


HOXD13_N298S DNA binding domain only search save
HOXD13_N298S Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAISKFIN KDKRRRISAA
51  TNLSERQVTI WFQNRRVKDK KIVSKLKDTV S


HOXD13_Q325K DNA binding domain only search save
HOXD13_Q325K Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAINKFIN KDKRRRISAA
51  TNLSERQVTI WFKNRRVKDK KIVSKLKDTV S


HOXD13_Q325R DNA binding domain only search save
HOXD13_Q325R Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAINKFIN KDKRRRISAA
51  TNLSERQVTI WFRNRRVKDK KIVSKLKDTV S


HOXD13_R306W DNA binding domain only search save
HOXD13_R306W Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAINKFIN KDKWRRISAA
51  TNLSERQVTI WFQNRRVKDK KIVSKLKDTV S


HOXD13_S316C DNA binding domain only search save
HOXD13_S316C Insert Sequence
1   VALNQPDMCV YRRGRKKRVP YTKLQLKELE NEYAINKFIN KDKRRRISAA
51  TNLCERQVTI WFQNRRVKDK KIVSKLKDTV S


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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