-Genomic Data for NR2E3 Links
Protein
NR2E3
UniPROBE Accession Number
UP00607
Species
Homo sapiens
Domain
zf-C4
Swiss-Prot
Q9Y5X4
Name and Synonyms
Name: photoreceptor-specific nuclear receptor.
Synonyms:ESCS, MGC49976, Nuclear receptor subfamily 2 group E member 3, Photoreceptor-specific nuclear receptor, PNR, rd7, Retina-specific nuclear receptor, RNR, RP37
IHOP
95150
NCBI RefSeq
NP_057430
Description
This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
JASPAR
None Available
-PBM Motif Data for NR2E3_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
AAAGATCA E.S. 0.496
TGATCTTT E.S. 0.496
Downloads
Download the zip of all NR2E3_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for NR2E3_G56R_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
GGGATCA.A E.S. 0.456
T.TGATCCC E.S. 0.456
Downloads
Download the zip of all NR2E3_G56R PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for NR2E3_R76Q_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
ATGAT.TC.A E.S. 0.416
T.GA.ATCAT E.S. 0.416
Downloads
Download the zip of all NR2E3_R76Q PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for NR2E3_R76W_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
ATAT.TA.TG E.S. 0.395
CA.TA.ATAT E.S. 0.395
Downloads
Download the zip of all NR2E3_R76W PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for NR2E3_R77Q_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
AAAGATCA E.S. 0.471
TGATCTTT E.S. 0.471
Downloads
Download the zip of all NR2E3_R77Q PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for NR2E3 (all alleles)
Downloads
Download the zip of all NR2E3 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-NR2E3 Datasets
Clone Clone Type Last Modified Save View
NR2E3_REF DNA binding domain only search save
NR2E3_REF Insert Sequence
1    PGRWGLGEDP TGVSPSLQCR VCGDSSSGKH YGIYACNGCS GFFKRSVRRR
51   LIYRCQVGAG MCPVDKAHRN QCQACRLKKC LQAGMNQDAV QNERQPRSTA
101  QVHLDSMES


NR2E3_G56R DNA binding domain only search save
NR2E3_G56R Insert Sequence
1    PGRWGLGEDP TGVSPSLQCR VCGDSSSRKH YGIYACNGCS GFFKRSVRRR
51   LIYRCQVGAG MCPVDKAHRN QCQACRLKKC LQAGMNQDAV QNERQPRSTA
101  QVHLDSMES


NR2E3_R76Q DNA binding domain only search save
NR2E3_R76Q Insert Sequence
1    PGRWGLGEDP TGVSPSLQCR VCGDSSSGKH YGIYACNGCS GFFKRSVQRR
51   LIYRCQVGAG MCPVDKAHRN QCQACRLKKC LQAGMNQDAV QNERQPRSTA
101  QVHLDSMES


NR2E3_R76W DNA binding domain only search save
NR2E3_R76W Insert Sequence
1    PGRWGLGEDP TGVSPSLQCR VCGDSSSGKH YGIYACNGCS GFFKRSVWRR
51   LIYRCQVGAG MCPVDKAHRN QCQACRLKKC LQAGMNQDAV QNERQPRSTA
101  QVHLDSMES


NR2E3_R77Q DNA binding domain only search save
NR2E3_R77Q Insert Sequence
1    PGRWGLGEDP TGVSPSLQCR VCGDSSSGKH YGIYACNGCS GFFKRSVRQR
51   LIYRCQVGAG MCPVDKAHRN QCQACRLKKC LQAGMNQDAV QNERQPRSTA
101  QVHLDSMES


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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