-Genomic Data for PAX4 Links
Protein
PAX4
UniPROBE Accession Number
UP00610
Species
Homo sapiens
Domain
PAX
Name and Synonyms
Name: paired box protein Pax-4.
Synonyms:KPD, MGC129960, MODY9, Paired box protein Pax-4
Description
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
PAX4 DNA binding domain
1   HRNRTIFSPG QAEALEKEFQ RGQYPDSVAR GKLAAATSLP EDTVRVWFSN
51  RRAKWRR
-PBM Motif Data for PAX4_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
CTAATTAG E.S. 0.496
CTAATTAG E.S. 0.496
Downloads
Download the zip of all PAX4_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX4_REF_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
C..CTAATTA E.S. 0.495
TAATTAG..G E.S. 0.495
Downloads
Download the zip of all PAX4_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX4_REF_R3
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
AATTAATT E.S. 0.496
AATTAATT E.S. 0.496
Downloads
Download the zip of all PAX4_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX4_R183C_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
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Top Kmer
GT.TAATTA E.S. 0.491
TAATTA.AC E.S. 0.491
Downloads
Download the zip of all PAX4_R183C PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX4_R192H_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CTAATTAG E.S. 0.499
CTAATTAG E.S. 0.499
Downloads
Download the zip of all PAX4_R192H PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX4_R192H_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CTAATTAG E.S. 0.498
CTAATTAG E.S. 0.498
Downloads
Download the zip of all PAX4_R192H PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX4_R192S_R2
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
CTAATTAG E.S. 0.498
CTAATTAG E.S. 0.498
Downloads
Download the zip of all PAX4_R192S PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PAX4_R192S_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available.  We apologize for the inconvenience.
PWM
Save
Top Kmer
CTAATTAG E.S. 0.497
CTAATTAG E.S. 0.497
Downloads
Download the zip of all PAX4_R192S PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for PAX4 (all alleles)
Downloads
Download the zip of all PAX4 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PAX4 Datasets
Clone Clone Type Last Modified Save View
PAX4_REF DNA binding domain only 2016-03-24 search save
PAX4_REF Insert Sequence
1    RQQIVRLAVS GMRPCDISRI LKVSNGCVSK ILGRYYRTGV LEPKGIGGSK
51   PRLATPPVVA RIAQLKGECP ALFAWEIQRQ LCAEGLCTQD KTPSVSSINR
101  VLRALQEDQG LPCTRLRSPA VLAPAVLTPH SGSETPRGTH PGTGHRNRTI
151  FSPSQAEALE KEFQRGQYPD SVARGKLATA TSLPEDTVRV WFSNRRAKWR
201  RQEKLKWEMQ LPGASQGL



PAX4_R183C DNA binding domain only 2016-03-24 search save
PAX4_R183C Insert Sequence
1    RQQIVRLAVS GMRPCDISRI LKVSNGCVSK ILGRYYRTGV LEPKGIGGSK
51   PRLATPPVVA RIAQLKGECP ALFAWEIQRQ LCAEGLCTQD KTPSVSSINR
101  VLRALQEDQG LPCTRLRSPA VLAPAVLTPH SGSETPRGTH PGTGHRNRTI
151  FSPSQAEALE KEFQCGQYPD SVARGKLATA TSLPEDTVRV WFSNRRAKWR
201  RQEKLKWEMQ LPGASQGL



PAX4_R192H DNA binding domain only 2016-03-24 search save
PAX4_R192H Insert Sequence
1    RQQIVRLAVS GMRPCDISRI LKVSNGCVSK ILGRYYRTGV LEPKGIGGSK
51   PRLATPPVVA RIAQLKGECP ALFAWEIQRQ LCAEGLCTQD KTPSVSSINR
101  VLRALQEDQG LPCTRLRSPA VLAPAVLTPH SGSETPRGTH PGTGHRNRTI
151  FSPSQAEALE KEFQRGQYPD SVAHGKLATA TSLPEDTVRV WFSNRRAKWR
201  RQEKLKWEMQ LPGASQGL



PAX4_R192S DNA binding domain only 2016-03-24 search save
PAX4_R192S Insert Sequence
1    RQQIVRLAVS GMRPCDISRI LKVSNGCVSK ILGRYYRTGV LEPKGIGGSK
51   PRLATPPVVA RIAQLKGECP ALFAWEIQRQ LCAEGLCTQD KTPSVSSINR
101  VLRALQEDQG LPCTRLRSPA VLAPAVLTPH SGSETPRGTH PGTGHRNRTI
151  FSPSQAEALE KEFQRGQYPD SVASGKLATA TSLPEDTVRV WFSNRRAKWR
201  RQEKLKWEMQ LPGASQGL



References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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