-Genomic Data for POU3F4 Links
Protein
POU3F4
UniPROBE Accession Number
UP00616
Species
Homo sapiens
Domain
POU
Swiss-Prot
P49335
Name and Synonyms
Name: POU domain, class 3, transcription factor 4.
Synonyms:Brain-4, BRAIN-4, Brain-specific homeobox/POU domain protein 4, BRN4, Brn-4, DFN3, DFNX2, Oct-9, Octamer-binding protein 9, Octamer-binding transcription factor 9, OTF9, OTF-9, POU domain, class 3, transcription factor 4
IHOP
91193
Description
This gene encodes a member of the POU-III class of neural transcription factors. This family member plays a role in inner ear development. The protein is thought to be involved in the mediation of epigenetic signals which induce striatal neuron-precursor differentiation. Mutations in this gene are associated with X chromosome-linked nonsyndromic mixed deafness. [provided by RefSeq, Dec 2012]
NCBI RefSeq
NP_000298
POU3F4 DNA binding domain
1   RKKRTSIEVS VKGVLETHFL KCPKPAAQEI SSLADSLQLE KEVVRVWFCN
51  RRQKEKR
JASPAR
None Available
-PBM Motif Data for POU3F4_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
ATTATGCA E.S. 0.497
TGCATAAT E.S. 0.497
Downloads
Download the zip of all POU3F4_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for POU3F4_A237G_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
ATTATGCA E.S. 0.495
TGCATAAT E.S. 0.495
Downloads
Download the zip of all POU3F4_A237G PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for POU3F4_A312V_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
TTAATTAA E.S. 0.497
TTAATTAA E.S. 0.497
Downloads
Download the zip of all POU3F4_A312V PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for POU3F4_R323G_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
ATTATGCA E.S. 0.496
TGCATAAT E.S. 0.496
Downloads
Download the zip of all POU3F4_R323G PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for POU3F4_V322M_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
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PWM
Save
Top Kmer
TTAATTAA E.S. 0.499
TTAATTAA E.S. 0.499
Downloads
Download the zip of all POU3F4_V322M PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for POU3F4 (all alleles)
Downloads
Download the zip of all POU3F4 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-POU3F4 Datasets
Clone Clone Type Last Modified Save View
POU3F4_REF DNA binding domain only search save
POU3F4_REF Insert Sequence
1    DHGELGSHHC QDHSDEETPT SDELEQFAKQ FKQRRIKLGF TQADVGLALG
51   TLYGNVFSQT TICRFEALQL SFKNMCKLKP LLNKWLEEAD SSTGSPTSID
101  KIAAQGRKRK KRTSIEVSVK GVLETHFLKC PKPAAQEISS LADSLQLEKE
151  VVRVWFCNRR QKEKRMTPPG DQQPHEVYSH TVKTDTSCHD L


POU3F4_A237G DNA binding domain only search save
POU3F4_A237G Insert Sequence
1    DHGELGSHHC QDHSDEETPT SDELEQFAKQ FKQRRIKLGF TQADVGLALG
51   TLYGNVFSQT TICRFEGLQL SFKNMCKLKP LLNKWLEEAD SSTGSPTSID
101  KIAAQGRKRK KRTSIEVSVK GVLETHFLKC PKPAAQEISS LVDSLQLEKE
151  VVRVWFCNRR QKEKRMTPPG DQQPHEVYSH TVKTDTSCHD L


POU3F4_A312V DNA binding domain only search save
POU3F4_A312V Insert Sequence
1    DHGELGSHHC QDHSDEETPT SDELEQFAKQ FKQRRIKLGF TQADVGLALG
51   TLYGNVFSQT TICRFEALQL SFKNMCKLKP LLNKWLEEAD SSTGSPTSID
101  KIAAQGRKRK KRTSIEVSVK GVLETHFLKC PKPAAQEISS LVDSLQLEKE
151  VVRVWFCNRR QKEKRMTPPG DQQPHEVYSH TVKTDTSCHD L


POU3F4_R323G DNA binding domain only search save
POU3F4_R323G Insert Sequence
1    DHGELGSHHC QDHSDEETPT SDELEQFAKQ FKQRRIKLGF TQADVGLALG
51   TLYGNVFSQT TICRFEALQL SFKNMCKLKP LLNKWLEEAD SSTGSPTSID
101  KIAAQGRKRK KRTSIEVSVK GVLETHFLKC PKPAAQEISS LADSLQLEKE
151  VVGVWFCNRR QKEKRMTPPG DQQPHEVYSH TVKTDTSCHD L


POU3F4_V322M DNA binding domain only search save
POU3F4_V322M Insert Sequence
1    DHGELGSHHC QDHSDEETPT SDELEQFAKQ FKQRRIKLGF TQADVGLALG
51   TLYGNVFSQT TICRFEALQL SFKNMCKLKP LLNKWLEEAD SSTGSPTSID
101  KIAAQGRKRK KRTSIEVSVK GVLETHFLKC PKPAAQEISS LADSLQLEKE
151  VMRVWFCNRR QKEKRMTPPG DQQPHEVYSH TVKTDTSCHD L


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


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