-Genomic Data for PROP1 Links
Protein
PROP1
UniPROBE Accession Number
UP00619
Species
Homo sapiens
Domain
Homeobox
Swiss-Prot
O75360
Name and Synonyms
Name: homeobox protein prophet of Pit-1.
Synonyms:Homeobox protein prophet of Pit-1, Pituitary-specific homeodomain factor, PROP-1
IHOP
91354
Description
This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone. [provided by RefSeq, Sep 2011]
NCBI RefSeq
NP_006252
PROP1 DNA binding domain
1   RRHRTTFNPA QLEQLESAFG RNQYPDIWAR EGLAQDTGLS EARIQVWFQN
51  RRAKQRK
JASPAR
None Available
-PBM Motif Data for PROP1_REF_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
AAT..AATTA E.S. 0.498
TAATT..ATT E.S. 0.498
Downloads
Download the zip of all PROP1_REF PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PROP1_R112Q_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
AA.T.AATTA E.S. 0.495
TAATT.A.TT E.S. 0.495
Downloads
Download the zip of all PROP1_R112Q PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PBM Motif Data for PROP1_R99Q_R1
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
Image Not Available. We apologize for the inconvenience.
PWM
Save
Top Kmer
AAT..AATTA E.S. 0.497
TAATT..ATT E.S. 0.497
Downloads
Download the zip of all PROP1_R99Q PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
Download Data for PROP1 (all alleles)
Downloads
Download the zip of all PROP1 PBM files, or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-PROP1 Datasets
Clone Clone Type Last Modified Save View
PROP1_REF DNA binding domain only search save
PROP1_REF Insert Sequence
1   FSPQGGQRGR PHSRRRHRTT FSPVQLEQLE SAFGRNQYPD IWARESLARD
51  TGLSEARIQV WFQNRRAKQR KQERSLLQPL AHLSPA


PROP1_R112Q DNA binding domain only search save
PROP1_R112Q Insert Sequence
1   FSPQGGQRGR PHSRRRHRTT FSPVQLEQLE SAFGRNQYPD IWARESLARD
51  TGLSEAMIQV WFQNRRAKQR KQERSLLQPL AHLSPA


PROP1_R99Q DNA binding domain only search save
PROP1_R99Q Insert Sequence
1   FSPQGGQRGR PHSRRRHRTT FSPVQLEQLE SAFGRNQYPD IWAQESLARD
51  TGLSEARIQV WFQNRRAKQR KQERSLLQPL AHLSPA


References
Data are analyzed by array designs with AMADID #s 030236, 015681 in Barrera et al., Science 2016


Supported Browsers:IE 7.0.6001.18000, Firefox 3.5.11, Google Chrome 5.0.375.125 beta