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| -Genomic Data for Foxa3 |
Links |
- Protein
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- UniPROBE Accession Number
- UP01365
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- Species
- Mus musculus
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- Domain
- Forkhead
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- Swiss-Prot
- P35584
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- Name and Synonyms
- Name: Hepatocyte nuclear factor 3-gamma.
Synonyms:Forkhead box protein A3, Hnf3g, Hnf-3g, HNF-3G, HNF-3-gamma, Tcf3g, Tcf-3g
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- IHOP
- 121713
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- NCBI RefSeq
- NP_032286
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- Description
- Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; activates GLUT2 transcription. Involved in regulation of neuronal-specific transcription. Involved in regulation of spermatogenesis; required for the maintenance of the testicular germ cell population and male fertility.
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- JASPAR
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None Available
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| -PBM Motif Data for Foxa3 |
- PBM-Derived DNA Binding Site Motif
(Seed-And-Wobble)
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- PWM
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Save
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- Top Kmer
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GTAAACAA E.S. 0.498
TTGTTTAC E.S. 0.498
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- Downloads
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Download the
zip
of all Foxa3 PBM files
or view the downloads directory for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -Foxa3 Datasets |
| Gene |
Clone Type |
Last Modified |
Save |
View |
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Foxa3 |
DNA binding domain only |
2017-05-12 |
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- Foxa3 Insert Sequence
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1 VHGKEMAKGY RRPLAHAKPP YSYISLITMA IQQAPGKMLT LSEIYQWIMD
51 LFPYYRENQQ RWQNSIRHSL SFNDCFVKVA RSPDKPGKGS YWALHPSSGN
101 MFENGCYLRR QKRFKLEEKA KKGNSATS
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- References
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Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017
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