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| -Genomic Data for Foxo3 |
Links |
- Protein
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- UniPROBE Accession Number
- UP01371
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- Species
- Mus musculus
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- Domain
- Forkhead
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- Swiss-Prot
- Q9WVH4
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- Name and Synonyms
- Name: forkhead box protein .
Synonyms:forkhead box O3a, 1110048B16Rik, 2010203A17Rik, C76856, Fkhr2, FKHRL1, Foxo3a
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- IHOP
- 129451
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- NCBI RefSeq
- NP_062714
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- Description
- Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
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- JASPAR
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None Available
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| -PBM Motif Data for Foxo3 |
- PBM-Derived DNA Binding Site Motif
(Seed-And-Wobble)
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- PWM
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Save
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- Top Kmer
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T.GTAAACA E.S. 0.498
TGTTTAC.A E.S. 0.498
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- Downloads
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Download the
zip
of all Foxo3 PBM files
or view the downloads directory for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -Foxo3 Datasets |
| Gene |
Clone Type |
Last Modified |
Save |
View |
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Foxo3 |
DNA binding domain only |
2017-05-12 |
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- Foxo3 Insert Sequence
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1 CTWPLQRPEL QASPAKPSGE TAADSMIPEE DDDEDDEDGG GRASSAMVIG
51 GGVSSTLGSG LLLEDSAMLL APGGQDLGSG PASAAGALSG GTPTQLQPQQ
101 PLPQPQPGAA GGSGQPRKCS SRRNAWGNLS YADLITRAIE SSPDKRLTLS
151 QIYEWMVRCV PYFKDKGDSN SSAGWKNSIR HNLSLHSRFM RVQNEGTGKS
201 SWWIINPDGG KSGKAPRRRA VSMDNSNKYT KSR
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- References
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Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017
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