-Genomic Data for Mafg Links
Protein
UniPROBE Accession Number
UP01375
Species
Mus musculus
Domain
BRLZ
Name and Synonyms
Name: Transcription factor MafG.
Synonyms:AA545192, C630022N07Rik, V-maf musculoaponeurotic fibrosarcoma oncogene homolog G
Description
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF- E2. Activates globin gene expression when associated with NF-E2. May be involved in signal transduction of extracellular H(+) (By similarity).
-PBM Motif Data for Mafg
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
AGTCAGCA
PWM
Save
Top Kmer
AGTCAGCA E.S. 0.495
TGCTGACT E.S. 0.495
Downloads
Download the zip of all Mafg PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-Mafg Datasets
Gene Clone Type Last Modified Save View
Mafg DNA binding domain only 2017-05-12 search save
Mafg Insert Sequence
1    EGNKALKVKR EPGENGTSLT DEELVTMSVR ELNQHLRGLS KEEIIQLKQR
51   RRTLKNRGYA ASCRVKRVTQ KEELEKQKAE LQQEVEKLAS ENASMKLELD
101  ALRSKYEALQ NFARTVARSP VAPARG



References
Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017


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