-Genomic Data for Tcfec Links
Protein
UniPROBE Accession Number
UP01400
Species
Mus musculus
Domain
HLH
Name and Synonyms
Name: Transcription factor EC.
Synonyms:BB107417, bHLHe34, MGC107474, mTFEC, Tfec, TFEC, TFE-C
Description
Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence) (By similarity). Binds to element F in an E-box sequence-specific manner (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form.
-PBM Motif Data for Tcfec
PBM-Derived DNA Binding Site Motif (Seed-And-Wobble)
CACGTGAC
PWM
Save
Top Kmer
CACGTGAC E.S. 0.500
GTCACGTG E.S. 0.500
Downloads
Download the zip of all Tcfec PBM files or view the downloads directory for individual files. Please note that the files which include probe sequence data are protected by an academic research use license, which can be viewed here.
-Tcfec Datasets
Gene Clone Type Last Modified Save View
Tcfec DNA binding domain only 2017-05-12 search save
Tcfec Insert Sequence
1    MTFDCRVCDQ TLKRAQPPAA SCMPLAEHEP MSPDSDAGCA GNPFTNLLAL
51   GKKDGAEKWH LSGSILDVYS DEQGISSANA GLTDAPCPSI LPMRKEIAET
101  DGRALAKERQ KKDNHNLIER RRRYNINYRI KELGTLIPKS NDPDMRWNKG
151  TILKASVDYI KWLQKEQQRA RELEHRQKKL EHANRQLRLR IQELEIQARA
201  HGLPILASLG TADVGTHITK QQTHPERNLG GCCLQLTPTQ GTSPEFYEQA
251  VAFSDPLSHF TDLSFSAALK EEQRLDGMLL SDTICPFGTD PLLSAISPAV
301  SKASSRSSLS SEDGDEL



References
Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017


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