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-Genomic Data for Tcfec |
Links |
- Protein
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- UniPROBE Accession Number
- UP01400
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- Species
- Mus musculus
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- Domain
- HLH
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- Swiss-Prot
- Q9WTW4
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- Name and Synonyms
- Name: Transcription factor EC.
Synonyms:BB107417, bHLHe34, MGC107474, mTFEC, Tfec, TFEC, TFE-C
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- IHOP
- 125395
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- NCBI RefSeq
- NP_112475
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- Description
- Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence) (By similarity). Binds to element F in an E-box sequence-specific manner (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo- or heterodimeric form.
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- JASPAR
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None Available
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-PBM Motif Data for Tcfec |
- PBM-Derived DNA Binding Site Motif
(Seed-And-Wobble)
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- PWM
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Save
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- Top Kmer
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CACGTGAC E.S. 0.500
GTCACGTG E.S. 0.500
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- Downloads
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Download the
zip
of all Tcfec PBM files
or view the downloads directory for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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-Tcfec Datasets |
Gene |
Clone Type |
Last Modified |
Save |
View |
Tcfec |
DNA binding domain only |
2017-05-12 |
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- Tcfec Insert Sequence
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1 MTFDCRVCDQ TLKRAQPPAA SCMPLAEHEP MSPDSDAGCA GNPFTNLLAL
51 GKKDGAEKWH LSGSILDVYS DEQGISSANA GLTDAPCPSI LPMRKEIAET 101 DGRALAKERQ KKDNHNLIER RRRYNINYRI KELGTLIPKS NDPDMRWNKG 151 TILKASVDYI KWLQKEQQRA RELEHRQKKL EHANRQLRLR IQELEIQARA 201 HGLPILASLG TADVGTHITK QQTHPERNLG GCCLQLTPTQ GTSPEFYEQA 251 VAFSDPLSHF TDLSFSAALK EEQRLDGMLL SDTICPFGTD PLLSAISPAV 301 SKASSRSSLS SEDGDEL
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- References
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Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017
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