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| -Genomic Data for Irf2 |
Links |
- Protein
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- UniPROBE Accession Number
- UP01405
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- Species
- Mus musculus
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- Domain
- IRF
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- Swiss-Prot
- P23906
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- Name and Synonyms
- Name: interferon regulatory factor 2.
Synonyms:9830146E22Rik, AI646973, Irf-2, IRF-2, MGC117893
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- IHOP
- 122146
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- NCBI RefSeq
- NP_032417
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- Description
- Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
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- JASPAR
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None Available
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| -PBM Motif Data for Irf2 |
- PBM-Derived DNA Binding Site Motif
(Seed-And-Wobble)
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- PWM
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Save
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- Top Kmer
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AAA..GAAAC E.S. 0.494
GTTTC..TTT E.S. 0.494
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- Downloads
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Download the
zip
of all Irf2 PBM files
or view the downloads directory for individual files.
Please note that the files which include probe sequence data are protected by an academic research use license,
which can be viewed here.
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| -Irf2 Datasets |
| Gene |
Clone Type |
Last Modified |
Save |
View |
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Irf2 |
DNA binding domain only |
2017-05-12 |
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- Irf2 Insert Sequence
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1 MPVERMRMRP WLEEQINSNT IPGLKWLNKE KKIFQIPWMH AARHGWDVEK
51 DAPLFRNWAI HTGKHQPGID KPDPKTWKAN FRCAMNSLPD IEEVKDRSIK
101 KGNNAFRVYR MLPLSERPSK KGKKPKTEK
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- References
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Data are analyzed by array designs with AMADID #s 016060, 015681 in Mariani et al., Cell Systems 2017
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